Have you ever wondered why Vitamin C research has resulted in conflicting findings? From our thousands of hours of analysis we have concluded that nutritional supplement research results are often pre-determined by the following factors:

1. Quality of Ingredients
2. Quantity administered
3. Regularity of dosage
4. Duration of consumption

We are not overlooking the basic methodological considerations like proper controls, placebo groups, and the appropriate analytical techniques, but the four factors above tend to influence in a major way the findings of the researchers.

Let us give you a simple analogy to make our point. Pretend that a researcher hypothesizes that water can be used to clean your body.

In order to test his hypothesis he selects a thousand people and gives them muddy sludge water out of a sewer. No matter how many subjects, how long the test or how much of this filthy water is given, the scientist is not going to conclude that water is appropriate for cleaning your body. Hence, the quality of the ingredients is important.

Now, let's give the subjects only pure and clean water to bath in, but they are given only one drop each. Again, the scientist is not going to find that water is appropriate for cleaning your body. Hence, the quantity of dosage is important.

Perhaps, the scientist provides pure water in a quantity appropriate for a bath, but he only allows the subjects to take a bath for three days throughout the month. Again, the scientist is not going to find that water is appropriate for cleaning your body. Hence, regularity of intake is important.

Finally, the subjects are given pure water in an amount that is appropriate for a bath and they are allowed to take the bath at least once a day. But, they can only bath for the first three days and the test for cleanliness will be done at the end of the month. You guessed it, the results are going to be mixed at best. Hence, the duration of the administration is important.

Such has been the case with Vitamin C research. Most research has measured the impact of pure ascorbic acid, a good ingredient, but not one that is readily absorbed by the human body without other synergistic elements and delivery systems. For example, an orange contains not only Vitamin C, but traces of Calcium, Folate, B1, etc. The more closely your supplement replicates nature as God created it the more your body will see it as a good thing to be absorbed.

Secondly, the quantities administered in most studies are far below those necessary for any viable results. The reason for this is that most researchers presume that the MDR established by the USDA is meaningful when in fact, the MDR barely sustains health, much less overcomes disease. Most analyses have focused on less than 1/2 gram of Vitamin C administered daily, whereas research that has reported significant results have administered 2 or more grams of Vitamin C daily.

Nutritional scientists claim that Vitamin C has a half life (loses 1/2 of its potency) in the body of about 30 - 60 minutes. Therefore, if Vitamin C is administered once a day, the results will most certainly be different than if the administration occurs every couple of hours throughout each day.

Finally, if the methodology of the research uses high quality ingredients, proper doses and is administered at the proper times, the length of time before results will be seen must be seriously evaluated. From our analysis of the research, it is clear that the impact of Vitamin C is not observable before at least a month of intake. Of course, the time period is dependent upon the significance of the health issue being addressed.

So, there you have it. All of the research on Vitamin C that we have evaluated and that uses high quality ingredients and delivery systems, administered in the proper dosage and multiple times a day for extended periods, has without exception found that Vitamin C has a significant impact on oxidization (disease) within human cells.

Don't be impressed by the Ph.D. or M.D. behind a researcher's name. Look instead at the quality of the methodology behind their research.

The following are some books on Vitamin C that are not only easy to read for the lay person, but they offer valuable perspectives on the significance of Vitamin C to your everyday health. Admittedly, much of the research cited contains the flaws mentioned in "A Note About Vitamin C Research," but they are good general guides to immerse yourself in when beginning your voyage to optimal health.

1. Curing the Incurable: Vitamin C, Infectious Diseases, and Toxins, 3rd Edition Paperback – August 1, 2011 by J. D. Levy.
2. Vitamin C: The Real Story, Paperback- 2008 by Steve Hickey and Andrew W. Saul.
3. Cancer and Vitamin C: 21st Century Edition, November 2017 by Ewan Cameron, Linus Pauling, Ewan M. Cameron.

Vitamin C-lipid metabolites: uptake and retention and effect on plasma C-reactive protein and oxidized LDL levels in healthy volunteers by Dario Pancorbo, Carlos Vazquez, and Mary Ann Fletcher, 2008

Absorption rates and free radical scavenging values of vitamin C-lipid metabolites in human lymphoblastic cells by Benjamin S Weeks and Pedro P Perez, 2007

1. Vitamin C and Infections,by Harri Hemilia, 2017.
2. Possible application of high-dose vitamin C in the prevention and therapy of coronavirus infection by Ba X. Hoang, Graeme Shaw, Willian Fang and Bo Han, 2020.
3. Role of vitamin C in preventing of COVID-19 infection, progression and severity, by Umar Shahbaz, Nazira Fatima, Samra Basharat, Asma Bibi, Xiaobin Yu, Muhammad Hussain and Maryam Nasrullah.
4. Discovery shows new Vitamin C Health Benefits, by David Stauth, 2004
5. Unwinding the potentials of Vitamin C in Covid-19 and other diseases: An updated review, by Nikhil Mehta,Purvi Pokharna, andSaritha R Shetty, 2022
6. Vitamin C in Human Health and Disease Effects, Mechanisms of Action, and New Guidance on Intake: by Wang Jay Lee.

Vitamin C Promotes Wound Healing: The Use of in Vitro Scratch Assays to Assess Re-Epithelialization by Benjamin S. Weeks, Ruiqin Fu and Mohammad Zaidi

1. Cardiovascular health through Vitamin C Intake, by Elizabeth Moxley, 2023
2. Therapeutic potential role of vitamin C in prevention and control of heart transplant rejection and cardiac allograft vasculopathy. A need for consideration by Idd J Kenedy, Jaynes F. Kabuhaya and Harold Mashauri, 2023
3. Effect of vitamin C on endothelial function in health and disease: A systematic review and meta-analysis of randomised controlled trials, by Ashor A.W., Lara J., Mathers J.C., Siervo M., 2014

1. Cytotoxicity of ascorbatelipoic acid, and other antioxidants in hollow fibre in vitro tumors by Casciari, J., Riordan, N. S. T. M. X., Jackson, J. & Riordan, H., 2001
2. Effects of high dose intravenous ascorbic acid on the level of inflammation in patients with rheumatoid arthritis by Mikirova, N., Rogers, A., Casciari, J. & Taylor, P., 2012.
3. High-Dose Vitamin C in Advanced-Stage Cancer Patients by Anna Zasowska-Nowak, Piotr Jan Nowak and Aleksandra Cialkowska-Rysz, 2021.
4. Intravenous vitamin C administration improves quality of life in breast cancer patients during chemo-radiotherapy and aftercare: results of a retrospective, multicentre, epidemiological cohort study in Germany, by Vollbracht, C. et al., 2011.
5. Pharmacological ascorbic acid supresses syngenic tumor growth and metastases in hormone-refractory prostate cancer by Pollard, H., Levine, M., Eidelman, O. & Pollard, M., 2012.
6. Pharmacologic ascorbic acid concentrations selectively kill cancer cells action as a pro-drug to deliver hydrogen peroxide to tissues: by Chen, Q et. al., 2005.
7. Stromal cell oxidation: a mechanism by which tumors obtain vitamin C. by Agus, D., Vera, J. & Golde, D., 1999.
8. Supplemental ascorbate in the supportive treatment of cancer Prolongation of survival times in terminal human cancer by Cameron, E., Pauling, L. & Leibovitz, B., 1979.
9. Targeting cancer vulnerabilities with high-dose vitamin C by Bryan Ngo, Justin M. Van Riper, Lewis C. Cantley and Jihye Yun, 2020.
10. Vitamin C deficiency in cancer patients by Mayland, C., Bennett, M. & Allan, K.,Palliat, 2005.